Summary:
Most of the patients of psoriasis have a chronic course with
the need for continuous control of disease activity. Patients
with moderate-to-severe disease generally require
phototherapy, photo-chamotherapy or systemic agents (e.g.
cyclosporine, methotrexate, oral retinoids, fumaric acid
esters) to control their disease adequately. In general these
therapeutic modalities have proven to be highly effective in
the treatment of psoriasis. However, potentially serious toxicity
can limit their long term use. In this respect, hydroxyurea