Summary:
Background: The aim of this study was to analyze the
effectiveness and morbidity of chemical sphincterotomy
by 0.2% glyceryl trinitrate (GTN) in the treatment of
chronic anal fissure. The main end points were symptom
relief, fissure healing and side effects.
Methods: A prospective study was conducted to see the
effectiveness and side effects of 0.2% glyceryl trinitrate in
the treatment of patients with chronic anal fissure
attending the outpatient department of surgery from
February 2004 to the end of February 2005. All the
patients were followed up at 2 weeks interval for 8 weeks.
The primary focus was fissure healing and the secondary
focus were on improvement of symptoms, need for
surgical sphincterotomy and side effects.