Abstract
In the last few decades, both hyperuricemia and gout have
increased markedly. Recent studies show new concept into
the transporters that handle uric acid in the kidney as well
as possible links between these transporters &
hyperuricemia. There are changes in the treatment of
established hyperuricemia. Febuxostat and PEGuricase are
two novel treatments that have been evaluated and shown
to be highly effective in the management of hyperuricemia.
Monosodium urate (MSU) crystals are the inducers of
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