Summary:
Background information: Polycystic ovaries (PCO) and
their clinical expression (polycystic ovary syndrome) are
conditions characterized by menstrual abnormality, clinical
and biochemical features of hyperandrogenism. It is the
killer of womanhood. Woman of any ethnic background
can present with PCOS.
Objectives: To find out demographic characteristics such
as age, BMI, clinical presentations like hirsutism, menstrual
cycle pattern and fertility status and the hormonal changes
like LH/FSH ratio and serum testosterone level.
Study design: A descriptive cross sectional study for 1 year
from December 2009 to November 2010.
Study setting: Outdoor Department of obstetrics and
gynaecology and center for Nuclear Medicine and
Ultrasonography (CNMU) Mymensingh Medical College
Hospital, Mymensingh.
Result: Total 55 patients were evaluated. Most common age
was 20-29 years (72.7%) with mean age 23.55 years and
mean BMI 27.12 kg/m2. Clinical presentations were in this
study hirsutism in 36.4%, irregular menstrual cycle in 63.6%
and subfertility in 56.3%. Laboratory findings revealed
testosterone level was more than normal range in 58% case,
LH/FSH ratio was increased (more than 1:1) in 58.2% cases,
26 cases had both increased testosterone level and increased
LH/FSH ratio. 17cases had testosterone level within normal
range and LH/FSH ratio less than 1:1.
Conclusion: There are significant relationship between
irregular menstrual cycle pattern and hormonal changes
such as testosterone level and LH/FSH ratio. There are also
significant relationship between BMI and hirsutism with
increased testosterone level.
Keywords: Polycystic ovary, irregular menstrual cycle,
Hirsutism, subfertility LH/FSH ratio, testosterone level.
(J Banagladesh Coll Phys Surg 2014; 32: 142-148)