Prolonged high fever is a common clinical problem and
sometimes the diagnosis is difficult, management can be a
challenge to the clinicians. Adult onset Still’s Disease is a
rare systemic inflammatory disorder of unknown etiology
that is responsible for a significant proportion of cases of
fever of unknown origin and can also have serious
musculoskeletal sequelae. The disease presents as a
diagnostic and therapeutic challenge to the clinicians and
clinical guidelines are lacking. The emergence of
classification criteria, discovery of better serological markers
and the application of new biological agents may all provide
the clinicians with significant tools for the diagnosis and
management of this complex disorder.
Key words: Adult Still’s Disease (ASD), Adult-onset Still’s
Disease (AOSD), arthritis, ferritin