Summary:
Kikuchi Fujimoto’s disease (KFD) is a rare, immunemediated,
self-limiting disorder with unique
histopathological features. KFD is usually seen in young
Asian females; however, cases have been reported
throughout the world and in all ethnicities. It has been
recognized that there is a rare association between Systemic
Lupus Erythematosus (SLE) and KFD via sporadic case
reports. The exact pathophysiological relationship between
these two diseases is still unclear. We report a case of a
young Asian female who presented with persistent fever
followed by development of lymphadenopathy and was
diagnosed as Kikuchi Fujimoto’s disease based on lymph
node biopsy. Although an SLE workup was done and she
initially did not meet the American Rheumatology
Association (ARA) diagnostic criteria for lupus.The lymph
node biopsy did not show typical features of SLE. At last
criteria of SLE became obvious with time and case was
diagnosed as SLE.