Summary:
The presence of antiphospholipid antibody (aPL) has been
clearly shown to have an adverse effect on pregnancy
outcome. These effects may be apparent in the first trimester,
presenting as recurrent pregnancy loss, or may be associated
with the later development of pre-eclampsia (PE), IUGR,
placental abruption, pre-term delivery, and intrauterine
death. Antiphospholipid antibodies accounts for 3-5% of
patients with second trimester repetitive pregnancy losses.
The frequency of foetal death & recurrent abortion in
untreated patient is greater than 90%.We will discuss here
a 26 years old pregnant lady who was diagnosed 06 months
prior to this pregnancy during pre conceptional counseling
as antiphospholipid syndrome (APLS), autoimmune
hypothyroidism and hypertension. She was on aspirin,
heparin & thyroxine and ovulation inducing drugs before
conception. After conception she was on close monitoring
by the Obstetrician and Medicine specialist and ultimately
on 36th week pregnancy was terminated by LSCS & a female
baby was delivered. However, although the live birth rate is
increased sevenfold, it should be acknowledged that these
births are associated with an increased rate of prematurity
and possible neonatal complications. The increased
incidence of pregnancy-related complications necessitates
the need for careful antenatal surveillance, and for delivery
to be conducted in a unit with facilities for operative delivery
and neonatal intensive care.
Key Words: Pregnancy, APS , recurrent foetal loss.
(J Bangladesh Coll Phys Surg 2016; 34: 160-163)