Summary:
Background: Gall bladder carcinoma (GBC) is the most
common biliary tract cancer. Delayed presentation and early
spread of tumor made it one of the lethal tumors with poor
prognosis.
Objective: The objective of this study is to find out the
incidence of GBC in thick walled gall bladder (GB) in
comparison with that of normal wall thickness.
Methods: This prospective study was carried out in Combined
Military Hospital (CMH) Dhaka, CMH Momenshahi and
CMH Ghatail during the period of June 2007 to June 2014.
A total 300 patients underwent cholecystectomy were studied
retrospectively. Diagnosis was confirmed by histopathological
examination.
Results: Out of 300 patients 254 (84.88%) were female (male
: female = 1:5.52), age range 28 to 79 years. Maximum
number of the patients fall into fourth and fifth decades. 42
(14%) patients were found to have thick walled GB by preoperative
sonography and during surgery.
Histopathologically 13 (4.33%) patients were diagnosed as
GBC. Maximum patient (52.33%) had chronic cholecystitis.
Incidence of malignancy were higher (84.62%) in patients
having thicke walled GB.
Conclusion: GBC may present as focal or diffuse asymmetric
wall thickening or even in GB having normal wall
thickness. As early diagnosis and effective treatment can
significantly reduce the morality and morbidity all specimen
should be examined histopathologically.
Key words: Cholecystectomy, Gall bladder carcinoma, Thick
walled gall bladder.
(J Bangladesh Coll Phys Surg 2016; 34: 193-198)