A 13 -year- old girl was admitted with a history of
generalized seizures since the age of 4 years and
abnormal involuntary movements right leg for 6
months prior to admission. Since then she was
diagnosed as a case of epilepsy and was treated with
tablet sodium valporate . She born by normal home
NVD. Since birth, all her mile stone of development
was normal except at the age of 8 month, she developed
visual impairment and was treated as corneal ulcer for
4 years. During examination, Trousseau’s sign was
present, tone of muscle of 4 limbs were increased,
hyperreflexia , planter bilaterally extensor and ataxic
gaits. Her both cornea were hazy with corneal scar.
Investigations revealed hypocalcaemia, hyperphosphataemia
but normal alkaline phosphatase and
renal function. A plain computed tomographic (CT)
head scan demonstrated extensive bilateral
calcification in the region of basal ganglia and cerebral
cortex (Figures 1 and 2).