Summary:
Background: Pleomorphic Adenoma is the most common
salivary gland tumour accounts 40-70% of all salivary gland
tumour and about 60-80% of the benign tumours and 60-
70% of all parotid tumours. There is no study conducted in
Bangladesh to observe the clinical and histological variation
of the tumour. This study presents 36 cases of Pleomorphic
adenoma collected over 11 months at the different territory
hospital of Dhaka city.
Design: Observational study (November’ 2011 to
September’ 2012)
Setting: Department of Oral and Maxillofacial Surgery
(Dhaka Dental College and Hospital, Bangabandhu Sheikh
Mujib Medical Universityl), Department of ENT and Head-
Neck Surgery (Dhaka Medical College and Hospital,
Bangabandhu Sheikh Mujib Medical University).
Method: The entire patient clinically and cytologically
diagnosed as Pleomorphic adenoma were selected. Data
were collected in a summarized data sheet. Then
histopathological types of them were analyzed from
excisional biopsized tissue.
Result: There were 36 patients of Pleomorphic adenoma
of which 24(66.67%) in Parotid glands, 4(11.11%) in
Submandibular glands and 8(22.22%) in minor salivary
glands. Among the respondents, female was predominant
20(55.56%) with ages were between 29 years to 65 years
old (mean age 44.83 ± 8.32 years) with most patients
(44.44%) in 41 to 50 years of life. In histophathological
study showed Stromal rich 38.89%, cell rich 36.11% and
classic 25%. Cuboidal cells were the most commonly found
cellular type followed by plasmacytoid and
spindle.Trabeculae and duct like structures were the most
frequent pattern by the epithelial cells.Myxoid and
Hyalinization were the most frequently found mesenchymal
like tissue.Cases presented with symptoms such as swelling
(100%), limitation of mouth opening, paesthesia and pain.
Conclusion: The knowledge about clinical presentation and
the immense variety of cells, architectures and
morphological characteristics present in Pleomorphic
adenoma of the salivary gland is essential for correct
diagnosis and prognosis. The need for improved diagnostic
facilities and upgrading of infrastructure was stressed.
Key words: Pleomorphic adenoma, Salivary gland, Parotid
gland, Benign tumor
(J Bangladesh Coll Phys Surg 2019; 37: 72-77)
DOI: https://doi.org/10.3329/jbcps.v37i2.40563