Summary:
Primary complement deficiencies are very rare and a case of
6 year old girl with complement 3 deficiency is reported here
who presented with recurrent infections and rash since her
early childhood. She had several episodes of respiratory tract
infections, urinary tract infections and various episodes of
gastro enteritis and was treated subsequently every time with
injectable antibiotics. Later she developed encysted hydropneumothorax
with mild pleural thickening with
compression collapse of adjacent right lung. On investigation
complement 3 level was found below normal both in the
patient and in her parents and younger sister. This case is
reporting here in order to disseminate the message that
underlying cause of recurrent infections could be primary
immunodeficiency (C3).
Key words: Compliment 3 (C3), Primary Immune deficiency
(PID), Membrane Attack Complex (MAC)
(J Bangladesh Coll Phys Surg 2020; 38: 101-104)
DOI: https://doi.org/10.3329/jbcps.v38i2.45636