Abstract:
Oral submucous fibrosis (OSMF) is a complex, debilitating,
and precancerous condition. Formerly restricted to the Indian
subcontinent, it is now frequently seen in the Asian
communities of the United Kingdom, the United States, and
other developed countries, and thus constitutes a severe global
health problem. Areca-nut, the well-known causative agent
of the disease, is now recognized as a group one carcinogen.
Several grading systems and management protocols have
been published in the literature to deal with this progressive
disease.Despite the numerous medical methods used in oral
sub mucous fibrosis management, sometimes surgical
intervention becomes inevitable. Here, we extensively
reviewed existing literature to discuss about incidence,
presentation, aetio-pathogenesis, medical and surgical
management with outcome of OSMF.
Keywords: Areca nut, Arecoline, Fibrous Band, Oral Submucous
Fibrosis, Reconstruction.
(J Bangladesh Coll Phys Surg 2020; 38: 135-144)
DOI: https://doi.org/10.3329/jbcps.v38i3.47061