Abstract:
Introduction: COVID-19 is a major threat to human beings.
Clinical characterization, rapid identification of cases and
isolation are vital for containments of rapidly spreading
disease. The objectives of the study were to evaluate the clinico
pathologic profile of Covid 19 positive Bangladeshi patients
and also to see their clinical outcome within defined period.
Methods: This cohort study on 201 Bangladeshi cases was
done in Combined Military Hospital, a tertiary level hospital
in Dhaka, Bangladesh from April 2020 to May 2020. Total
201 COVID-19 cases were enrolled after getting the result
positive for RT-PCR. After collection, data were analysed to
show the characteristics of Covid 19 and their outcome after
treatment.
Results: Among 201 cases, 180 (90%) were male and 21
(10%) were female. The most prevalent affected age groups
were 71 (35.5%) patients in 26-35 years age, 54 (27%) in 16-
25 years, 49 (24.5%) in 35-45 years. Mean age is 32.2±2.
Among the total cases, 146 (73%) have positive history of
contact, 37 (18.5%) have no history of any contact, 8 (4%)
denied any contact with COVID-19 patients. Regarding
clinical presentations, 67 (33.5%) patients presented with
only one symptoms, 125 (62.5%) had multiple symptoms
and 9 (4.5%) cases were asymptomatic. 154 (77%) patients
presented with fever. Other presentations were cough 71
(35.5%), headache 27 (13.5%), myalgia 25 (12.5%), sore
throat 25 (12.5%), malaise 15 (7.5%), respiratory distress 11
(5.5%). Respiratory system was the dominant domain of
clinical presentation. Leukopenia was presented by 12 patients
and 12 had lymphopenia. 18 patients had mild
thrombocytopenia. Pulse oxymetry showed oxygen saturation
below 88% in 12 cases. After oxygen therapy 7 cases were
improved and 5 cases were shifted to Corona ICU as their
saturation fell below 70. These 5 patients are categorised as
severe disease, rest 196 patients were mild in nature.
Conclusion: COVID 19 affects male more than female.
Common symptoms are fever, cough, headache, myalgia,
sore throat, malaise, respiratory distress. Respiratory system is
the dominant domain of clinical presentation. ICU support
was needed in 2.5 % cases and death rate was 1% which was
associated with comorbidity of CKD.
Key Words: Bangladeshi patients, COVID 19, Cohort study,
RT PCR.
(J Bangladesh Coll Phys Surg 2020; 38: 37-42)
DOI: https://doi.org/10.3329/jbcps.v38i0.47346