Summary:
Objective: A modification of Friedewald’s formula was
proposed to calculate LDL cholesterol in Bangladeshi
population up to serum triglyceride concentration of 1000
mg/dL. The aim of this study was to validate the modification
of Friedewald’s formula in Bangladeshi population.
Methods: Serum total cholesterol, triglyceride, high-density
lipoprotein cholesterol and low-density lipoprotein
cholesterol concentrations were measured in specimens
obtained form 314 adult Bangladeshi subjects selected
conveniently. LDL cholesterol concentrations were also
calculated by modified Friedewald’s formula and original
Friedewald’s formula. Results were expressed as mean ±
SD and calculated LDL cholesterol was compared with
measured LDL cholesterol by two-tailed paired t test and
Pearson’s correlation coefficient (r).
Results: The mean ± SD of measured LDL cholesterol was
138.3 ± 54.58 mg/dL. LDL cholesterol calculated by